产品货号：
Z14550
中文名称：
FEZ1抗体
英文名称：
Anti-FEZ1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-FEZ1 Antibody |
| 指标别名 | FEZ1,Zygin 1,Zygin I |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB |
| 基因名称 | FEZ1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | FEZ1 antibody was raised against a 19 amino acid synthetic peptide from near the carboxy terminus of human FEZ1.The immunogen is located within amino acids 270 - 320 of FEZ1. |
| 计算分子量 | 45kDa |
| 成分 | FEZ1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | FEZ1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Similar to its C.elegans homolog UNC-76,mammalian FEZ1,an abundant membrane protein and protein kinase C (PKC)-Z substrate,is involved in axonal guidance.Following phosphorylation by PKC-Z,FEZ1 translocates from the plasma membrane to the cytoplasm.FEZ1 is then able to interact with a number of proteins involved in axonal outgrowth and cellular transport such as DISC1,a candidate gene for schizophrenia,as well as kinesin-1,a microtubule-based motor protein.FEZ1 also interacts with proteins involved in transcriptional regulation and chromatin remodeling,suggesting that FEZ1 may have nuclear regulatory functions in addition to those for neuronal development.At least two distinct isoforms of FEZ1 are known to exist. |
| Uniprot ID | Q99689 |
| 基因名全称 | Fasciculation and elongation protein zeta 1 (zygin I) |
| 蛋白名全称 | Fasciculation and elongation protein zeta 1 (zygin I) |
| 推荐稀释比 | FEZ1 antibody can be used for the detection of FEZ1 by Western blot at 0.5 ～ 1μg/mL.Despite its predicted molecular weight,FEZ1 will often run at higher molecular weight in SDS-PAGE.Antibody validated:Western Blot in human samples.All other applications and species not yet tested. |
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